Brand: Macrene Actives

Nature and science meet in this exceptional face cream from noted NYC dermatologist Macrene Alexiades, MD PhD FAAD. This all-in-one transformative moisturizer was inspired by Nobel Prize-winning research on DNA repair molecules, with a goal of improving all aspects of skin health. The cream combats redness, hyperpigmentation, dryness, and puffiness through a suite of plant-derived active ingredients—many of which are organically grown on Dr. Alexiades' Hudson Valley farm in Upstate New York. Models may have Dr. Alexiades on speed dial, but anyone can benefit from her expertise in a daily skin care regimen.

- Copper peptides, resveratrol, and amino acids minimize fine lines and wrinkles.
- Glucosamine, ergothioneine, arginine treat hyperpigmentation for even-toned skin.
- Mushroom extract, red algae, and plant polyphenols improve skin quality.
- Caffeine, coffee seed, yerba mate, and cacao de-puff and address undereye circles.
- Free of gluten, silicones, petrolatum, talc, mica, phthalates, parabens, sulfates, and fragrance.
- Vegan and made with USDA certified organic ingredients.

Before Use

Read the product packaging for current ingredients, directions, and warnings. Manufacturer formulas and packaging may change. Check the selected shade, size, or volume before ordering. Do not use an ingredient to which you know you are allergic.

Shipping and Returns

Free standard U.S. shipping. Estimated handling: 1–3 business days; estimated transit: 6–9 business days. Eligible returns and exchanges may be requested within 30 calendar days after delivery. Ordinary beauty-product returns must remain unopened and unused, with any supplied hygiene seals intact. Defective, damaged, or incorrect items are reviewed separately. Read our Shipping Policy and Return and Refund Policy for the full conditions.